Capabilities

Overall description of capabilities

Project Timeline: 7/1/2004 - 6/30/2007

Active and secondhand smoke (SHS) cause low birth weight, miscarriage, preterm birth, fetal and infant death, as well as other adverse pregnancy outcomes. Pregnant women, especially those of minority populations, are priority population for tobacco control in California. However, no objective data exist on the extent of tobacco exposure among minority pregnant women in California. This study used a biological measure - serum cotinine, a metabolite of nicotine found in blood - to assess active smoke and SHS exposure levels during mid-pregnancy in ten minority populations (Native Americans, Chinese, Japanese, Koreans, Filipinos, Cambodians, Vietnamese, Laotians, Asian Indians, and Samoans), compared to cotinine levels in pregnant Mexican Hispanics, Whites, and Blacks.

The study population was made up of 3966 women were enrolled in California's Prenatal Screening Program between 2000 and 2002, is prenatal care providers were located in the southern most part of California in Orange, San Diego, and Imperial counties, and whose blood was saved and frozen after testing and one of the state’s regional prenatal screening laboratories. Approximately 75% of all women delivering live births enrolled in the prenatal screening program during these years. Minority populations that showed a low smoking rate mid-pregnancy any concomitant low exposure to SHS were Chinese, Filipinos, and Laotians. Other minority populations that had a low or mid-level smoking rates and comparatively high exposure to SHS were Asian Indians, Vietnamese, and Cambodians, as well as Hispanics. These are groups in whose steps to protect pregnant women from SHS were likely not in place or ineffective. This is a steep contrast to whites who have high rates of smoking yet very low SHS exposure. In this study population, mean infant birth weight went down by 41 grams per log increase in cotinine when selected confounders were controlled. We conducted analysis determine if there was any evidence to suggest that SHS lowered mean birth weight more than one minority population than another and could not find any important differences between groups. These analyses, however, were limited by small sample size.

Projects

  1. Reduce Exposure to Unhealthy Air in the Imperial Valley, California near the U.S.-Mexico Border
  2. Neuro-Developmental Disabilities Screening and Assessment in Uganda
  3. Genome-Wide Association Study of Childhood Leukemia by Hispanic Status
  4. Characterization of CFTR Mutations Among Non-White CF Patients
  5. Building Capacity for Health Impact Assessment at State and Territorial Health Agencies
  6. Perinatal Exposure to Airborne Pollutants and Associations with Autism Phenotype
  7. Designing a Next Generation Science Standards Ready Air Quality Science High School Curriculum (Phase I and II)
  8. Social and Climate Change Migration Policy: Government of Tuvalu (South Pacific)
  9. Tobacco and cannabis exposure during pregnancy in six race/ethnic subgroups in California
  10. Studying Mothers and their Children at Risk from In Utero Exposure to Grandmaternal Smoking
  11. Public Health Effects of Increased Prescribe Burns for Wildlife Management
  12. East Bay Diesel Exposures Project (EBDEP)
  13. Expanding California Biomonitoring Database through Statewide Surveillance and Targeted Population Studies
  14. California Region Exposure Study 3 (CARE-3)
  15. California Region Exposure Study 2 (CARE-2)
  16. California Region Exposure Study I (CARE-LA)
  17. California's Strategic Plan Implementation Grants for Asthma
  18. Environmental Health Symposium for Promotores and Community Health Workers
  19. Palos Verdes Shelf Fish Contamination Project
  20. San Francisco Bay Fish Project
  21. Improve Low Rates of Childhood Lead Screening Amongst Health Care Providers
  22. Effectiveness of a Large Prenatal Tobacco Reduction Program
  23. California's Childhood Lead Poisoning Prevention Program
  24. Collection of Dried Blood Spots from Children for the Examination of CMV
  25. PBDE/Breast Milk Monitoring
  26. Early Childhood Mortality Study
  27. Preterm Markers Study-2006/07
  28. Maternal and Infant Genetic Contributions to Preterm Birth: the Inflammatory Response
  29. Preterm Markers Study-2009/10
  30. Development of a Research-Ready Pregnancy and Newborn Biobank in California
  31. National Newborn Screening and Genetics Resource Center
  32. Newborn Blood Spots, Collaborative Project with UCD Public Health Sciences Department
  33. Environmental and Molecular Epidemiology of Childhood Leukemia
  34. Evaluation of the Partnership for Smoke-Free Families Program
  35. Genetic Contributions to Preterm Birth Study
  36. Outcome Prediction in Children with Positive California Cystic Fibrosis Newborn Screening
  37. Prenatal and Neonatal Biologic Markers for Autism
  38. Ascertain Environmental Exposure During Pregnancy
  39. Enhancing the California Environmental Contaminant Biomonitoring Program
  40. CA Title 17 Analysis: Training/Certifying Renovation, Remodeling, and Painting Activities
  41. Children's Health Initiative - Impacts of Childhood Asthma in California
  42. Prenatal Smoke Exposure and Age at Menarche
  43. Selection In Utero: A Test of Competing Explanations
  44. iCARE General Population File
  45. Case-Control Study of Maternal and Infant Genetic Contributions to Preterm Birth
  46. California's Chronic Disease Environmental Health Surveillance System
  47. Design of California's Response and Surveillance System for Childhood Lead Exposures (RASSCLE II) System
  48. Data Mapping California's Blood Lead Testing Reports
  49. California Electronic Blood Lead Reporting Security and Data Transmission Upgrades
  50. Cystic Fibrosis Foundation Patient Registry Data Analysis