Capabilities

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Capability: Capabilities

Project Timeline: 3/12/2009-9/30/2010

Sequoia Foundation partnered with the California Department of Public Health, Genetic Disease Screening Program to conduct a population-based control study to examine the maternal and infant genetic contributions to preterm birth. Specifically, Sequoia Foundation pilot tested a MS-Access database developed by the CDC designed for this project; data entered over 1,000 medical records and linked this data with birth certificates, laboratory data, and prenatal and newborn screening records; developed the data dictionary to accompany this dataset; developed the master dataset; and sent the final de-identified dataset to the CDC. Results from the study would allow a comparative assessment of the contribution of both maternal and fetal genotypes in a single study, and would also assess potential maternal and/or infant gene-gene interactions (maternal-maternal, infant-infant, maternal-infant) and potential maternal and/or infant gene-environment interactions that modify the risk of preterm birth.

Projects

  1. Development of a Research-Ready Pregnancy and Newborn Biobank in California
  2. National Newborn Screening and Genetics Resource Center
  3. Newborn Blood Spots, Collaborative Project with UCD Public Health Sciences Department
  4. Environmental and Molecular Epidemiology of Childhood Leukemia
  5. Evaluation of the Partnership for Smoke-Free Families Program
  6. Genetic Contributions to Preterm Birth Study
  7. Outcome Prediction in Children with Positive California Cystic Fibrosis Newborn Screening
  8. Prenatal and Neonatal Biologic Markers for Autism
  9. Ascertain Environmental Exposure During Pregnancy
  10. Enhancing the California Environmental Contaminant Biomonitoring Program
  11. CA Title 17 Analysis: Training/Certifying Renovation, Remodeling, and Painting Activities
  12. Children's Health Initiative - Impacts of Childhood Asthma in California
  13. Prenatal Smoke Exposure and Age at Menarche
  14. Selection In Utero: A Test of Competing Explanations
  15. iCARE General Population File
  16. Case-Control Study of Maternal and Infant Genetic Contributions to Preterm Birth
  17. California's Chronic Disease Environmental Health Surveillance System
  18. Design of California's Response and Surveillance System for Childhood Lead Exposures (RASSCLE II) System
  19. Data Mapping California's Blood Lead Testing Reports
  20. California Electronic Blood Lead Reporting Security and Data Transmission Upgrades
  21. Cystic Fibrosis Foundation Patient Registry Data Analysis

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